Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518652 | 0.87 | AOC3 (0.40) | SMN1; SMN2AOC3ALDH1A1MAPK1MEN1 | |
| SCHEMBL11515083 | 0.82 | RAB9A (0.44) | SMN1; SMN2AOC3ALDH1A1MAPK1MEN1 | |
| SCHEMBL11517124 | 0.81 | AOC3 (0.37) | SMN1; SMN2AOC3ALDH1A1MAPK1MEN1 | |
| SCHEMBL11514019 | 0.81 | AOC3 (0.43) | SMN1; SMN2AOC3MAPK1MEN1KMT2A | |
| SCHEMBL11516126 | 0.79 | AOC3 (0.37) | SMN1; SMN2AOC3ALDH1A1MEN1KMT2A | |
| SCHEMBL11516665 | 0.77 | MAPT (0.45) | SMN1; SMN2AOC3ALDH1A1MEN1KMT2A | |
| SCHEMBL11515470 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2AOC3MEN1KMT2ANPC1 | |
| SCHEMBL11514454 | 0.73 | AOC3 (0.53) | SMN1; SMN2AOC3MEN1KMT2ARAB9A | |
| SCHEMBL11516954 | 0.70 | AOC3 (0.34) | SMN1; SMN2AOC3ALDH1A1MEN1KMT2A | |
| SCHEMBL11516190 | 0.70 | AOC3 (0.45) | SMN1; SMN2AOC3ALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |