Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514019 | 0.89 | AOC3 (0.43) | AOC3MAPK1MEN1KMT2AESR1 | |
| SCHEMBL11516376 | 0.87 | SMN1; SMN2 (0.41) | AOC3MAPK1MEN1KMT2AESR1 | |
| SCHEMBL11515027 | 0.82 | AOC3 (0.47) | AOC3RAB9ASMN1; SMN2 | |
| SCHEMBL11515809 | 0.79 | AOC3 (0.41) | AOC3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11516165 | 0.73 | AOC3 (0.43) | AOC3MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL11516529 | 0.71 | AOC3 (0.51) | AOC3MEN1KMT2ARAB9A | |
| SCHEMBL11515890 | 0.70 | AOC3 (0.39) | AOC3RAB9AALDH1A1 | |
| SCHEMBL11517524 | 0.70 | TRPM8 (0.45) | AOC3 | |
| SCHEMBL11517973 | 0.69 | AOC3 (0.46) | AOC3ALDH1A1 | |
| SCHEMBL11519430 | 0.69 | AOC3 (0.44) | AOC3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |