Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL5609245 | 0.98 | LMNA (0.56) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL6656414 | 0.87 | CA1 (0.41) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL8508528 | 0.86 | LMNA (0.58) | LMNAF2TSHRTDP1TP53 | |
| Benzene SCHEMBL27793442 | 0.85 | LMNA (0.70) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL52413 | 0.85 | LMNA (0.70) | LMNAF2TSHRTDP1TP53 | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.85 | LMNA (0.70) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL6656417 | 0.84 | TSHR (0.55) | TSHRTP53ALDH1A1MAPTCES2 | |
| Benzoyl Chloride SCHEMBL28645107 | 0.84 | LMNA (0.56) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL1534569 | 0.82 | LMNA (0.67) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL2591454 | 0.82 | LMNA (0.67) | LMNAF2TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017271-A1 | Process for the preparation of escitalopram | Aurobindo Pharma Limited (IN) | 2009-01-21 | — | — | EP | claimed |
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2023-11-16 | — | — | US | disclosed |
| CN-116669725-A | Novel aminopyridine and use thereof in the treatment of cancer | 奥克兰联合服务有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4217357-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | Auckland Uniservices Limited (NZ) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022064430-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-03-31 | — | — | WO | disclosed |
| WO-2021013163-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (CN) | 2021-01-28 | — | — | WO | disclosed |
| CN-106232214-B | Composite polyamide membrane post-treated with nitrous acid | 陶氏环球技术有限责任公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-105848758-B | Separation of hydrocarbons from aqueous mixtures using fouling resistant reverse osmosis membranes | 陶氏环球技术有限责任公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-110167982-A | The manufacturing method of block copolymer and block copolymer | 电化株式会社 | 2019-08-23 | — | — | CN | disclosed |
| EP-3108900-B1 | PROTOTYPE SYSTEMS OF THERANOSTIC BIOMARKERS FOR IN VIVO MOLECULAR MANAGEMENT OF CANCER | EPOS IASIS RES AND DEVELOPMENT LTD (CY) | 2019-04-24 | — | — | EP | disclosed |
| EP-0434708-A1 | PROCESS FOR PRODUCING DIPEPTIDES FROM NON-PROTEINOGENIC AMINO ACIDS WITH TERMINAL NITROGEN ATOMS. | BASF AG (DE) | 1991-07-03 | — | — | EP | disclosed |
| WO-1990003387-A1 | PROCESS FOR PRODUCING DIPEPTIDES FROM NON-PROTEINOGENIC AMINO ACIDS WITH TERMINAL NITROGEN ATOMS | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-05 | — | — | WO | disclosed |
| US-4665171-A | CARBACEPHALOSPORINS | HARVARD UNIVERSITY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |
| US-4460579-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0000473-A1 | Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives | Technobiotic Ltd. (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4138397-A | BACTERICIDES | RICHARDSON-MERRELL INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4053591-A | 5-DEOXY-4,6-DI-O-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, METHODS FOR THEIR MANUFACTURE, METHOD FOR THEIR USE AS ANTIBACTERIAL AGENTS AND COMPOSITIONS USEFUL THEREFOR | SCHERING CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4016146-A | Phenethylamine antigenic conjugates, their preparation, antibodies, and use | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1977-04-05 | — | — | US | disclosed |
| US-3996344-A | Phenethylamine antigenic conjugates, their preparation, antibodies and use | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | DCK, DTYMK, TYMP | LMNA 1848/4885F2 4154/4885TSHR 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.