Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605090 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2EPHX1ATM | |
| SCHEMBL27647947 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2EPHX1ATM | |
| SCHEMBL16298724 | 0.83 | EPHX1 (0.46) | PLA2G2APLA2G5TAS1R3TAS1R1BIRC2 | |
| SCHEMBL13519757 | 0.83 | EPHX1 (0.46) | PLA2G2APLA2G5TAS1R3TAS1R1BIRC2 | |
| SCHEMBL16116963 | 0.81 | KMT2A (0.54) | PLA2G2APLA2G5BIRC2MEN1KMT2A | |
| SCHEMBL14116525 | 0.81 | BIRC2 (0.45) | PLA2G2APLA2G5TAS1R3TAS1R1BIRC2 | |
| SCHEMBL16549952 | 0.81 | PLA2G10 (0.58) | PLA2G2APLA2G5MEN1KMT2A | |
| SCHEMBL14373742 | 0.81 | ALDH1A1 (0.50) | PLA2G2APLA2G5BIRC2ALDH1A1EPHX1 | |
| SCHEMBL11675839 | 0.81 | ALDH1A1 (0.50) | PLA2G2APLA2G5BIRC2ALDH1A1EPHX1 | |
| SCHEMBL11675841 | 0.81 | ALDH1A1 (0.50) | PLA2G2APLA2G5BIRC2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159980-A | Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-3947569-A | Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |