SCHEMBL11516772

SCHEMBL11516772

CCCOc1ccc2c(c1)C(C)(C)C(C)N2C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.38
BCHE P06276 2/20 0.38
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
PDK2 Q15119 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA12 O43570 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11514825 0.95 ACHE (0.38) ACHEBCHEMAPTALDH1A1PDK2
SCHEMBL11518023 0.90 ACHE (0.39) ACHEBCHEMAPTALDH1A1KMT2A
SCHEMBL11515565 0.75 KMT2A (0.46) ACHEBCHEMAPTALDH1A1KMT2A
SCHEMBL26024106 0.68 POLB (0.44) MAPTKMT2AMEN1CA1CA2
SCHEMBL11514660 0.66 MAOA (0.44) MAPTALDH1A1CACNA1BAPBA1PDK2
SCHEMBL11514223 0.65 KMT2A (0.36) ACHEBCHEMAPTALDH1A1KMT2A
SCHEMBL11514225 0.64 SMN1; SMN2 (0.36) ACHEBCHEMAOB
SCHEMBL5860140 0.64 PPARG (0.56) MAPTALDH1A1PDK2CA1CA2
Iodide SCHEMBL11816126 0.63 BCHE (0.37) BCHEMAPTALDH1A1KMT2AMEN1
SCHEMBL18199319 0.62 ERN1 (0.50) MAPTALDH1A1KMT2AMEN1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4145537-A BENZOTHIAZOLIUM DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed