Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20040004 | 0.89 | DNM1 (0.63) | DNM1ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10003570 | 0.87 | DNM1 (0.50) | DNM1ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL8953593 | 0.87 | DNM1 (0.50) | DNM1ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL25872066 | 0.81 | DNM1 (0.77) | DNM1ALDH1A1TLR2HTTCNR1 | |
| SCHEMBL31481827 | 0.81 | DNM1 (0.77) | DNM1ALDH1A1TLR2HTTCNR1 | |
| SCHEMBL1922643 | 0.81 | DNM1 (0.59) | DNM1ALDH1A1TLR2CNR1CNR2 | |
| SCHEMBL13978176 | 0.81 | DNM1 (0.77) | DNM1ALDH1A1TLR2HTTCNR1 | |
| SCHEMBL3502221 | 0.81 | DNM1 (0.59) | DNM1ALDH1A1TLR2CNR1CNR2 | |
| SCHEMBL2352070 | 0.79 | DNM1 (0.62) | DNM1ALDH1A1TLR2MEN1KMT2A | |
| SCHEMBL7628426 | 0.79 | DNM1 (0.62) | DNM1ALDH1A1TLR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154931-A | Process for the preparation of cyclic ureas | THE UPJOHN COMPANY (US) | 1979-05-15 | — | — | US | disclosed |