Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22915890 | 0.81 | KDM4E (0.47) | KDM4ENAMPTHTR2CPTGS1GRM5 | |
| SCHEMBL31595886 | 0.77 | NAMPT (0.37) | KDM4ENAMPTHTR2CKCNH2 | |
| SCHEMBL22915971 | 0.75 | SLC6A7 (0.52) | KDM4ENAMPTHTR2CSMN1; SMN2 | |
| SCHEMBL1994788 | 0.75 | NAMPT (0.38) | KDM4ENAMPTHTR2CADRA1AKCNH2 | |
| SCHEMBL22915967 | 0.75 | MAPK1 (0.50) | KDM4ENAMPT | |
| SCHEMBL11518308 | 0.74 | TMPRSS2 (0.42) | NAMPTHTR2CTMPRSS2 | |
| SCHEMBL22916009 | 0.73 | NPC1 (0.47) | KDM4E | |
| Hydrochloric Acid SCHEMBL11518596 | 0.73 | TMPRSS2 (0.41) | NAMPTHTR2CTMPRSS2 | |
| SCHEMBL11518591 | 0.73 | AKT1 (0.31) | HTR2C | |
| SCHEMBL11515050 | 0.73 | AKT1 (0.31) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |