Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11518596 | 0.98 | TMPRSS2 (0.41) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| SCHEMBL31595886 | 0.84 | NAMPT (0.37) | ADRA2ANAMPTAKT1HTR2C | |
| SCHEMBL1994788 | 0.79 | NAMPT (0.38) | ADRA2ANAMPTAKT1HTR2C | |
| SCHEMBL12662820 | 0.77 | BAZ2B (0.43) | LMNANAMPT | |
| SCHEMBL11518591 | 0.77 | AKT1 (0.31) | AKT1HTR2C | |
| SCHEMBL11515050 | 0.77 | AKT1 (0.31) | AKT1HTR2C | |
| SCHEMBL11517246 | 0.74 | NPSR1 (0.47) | TMPRSS2NAMPTHTR2C | |
| SCHEMBL11515901 | 0.74 | MEN1 (0.43) | LMNANAMPTAKT1HTR2C | |
| SCHEMBL11515494 | 0.74 | BAZ2B (0.43) | NAMPTAKT1HTR2CF2 | |
| SCHEMBL22915890 | 0.72 | KDM4E (0.47) | NAMPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |