Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.68 |
| ▸ | CNR1 | P21554 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | MTOR | P42345 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11522517 | 0.85 | CNR2 (0.59) | CNR2CNR1TSHRLMNACYP1A2 | |
| SCHEMBL11518423 | 0.84 | TSHR (0.60) | CNR2CNR1TSHRLMNACYP1A2 | |
| SCHEMBL11520081 | 0.84 | PTGS1 (0.80) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11522535 | 0.83 | LMNA (0.76) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11518964 | 0.82 | LMNA (0.62) | CNR2CNR1TSHRLMNACYP1A2 | |
| SCHEMBL12949361 | 0.82 | LMNA (0.80) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1082631 | 0.81 | HIF1A (1.00) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL11517674 | 0.80 | LMNA (0.59) | CNR2CNR1TSHRLMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL8646699 | 0.80 | HIF1A (0.98) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23391007 | 0.79 | LMNA (0.83) | CNR2TSHRLMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |