Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11517674 | 0.90 | LMNA (0.59) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11519435 | 0.87 | LMNA (0.57) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| Hydrochloric Acid SCHEMBL11517541 | 0.86 | LMNA (0.56) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11519530 | 0.86 | LMNA (0.56) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11521766 | 0.85 | LMNA (0.57) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11518065 | 0.85 | PTGS2 (0.54) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11518423 | 0.84 | TSHR (0.60) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11523712 | 0.83 | LMNA (0.52) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| Hydrochloric Acid SCHEMBL11517819 | 0.83 | AKR1C3 (0.58) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| Hydrochloric Acid SCHEMBL11522517 | 0.82 | CNR2 (0.59) | LMNACYP1A2CYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |