Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445166 | 0.88 | MAPT (0.74) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL3631370 | 0.85 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL6129230 | 0.80 | ALDH1A1 (0.68) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL23673651 | 0.80 | MAPT (0.47) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL14747892 | 0.76 | MAPT (0.43) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL15432005 | 0.75 | MAPT (0.61) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL12618676 | 0.72 | ALDH1A1 (0.77) | MAPTALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL15448153 | 0.71 | MAPT (0.55) | MAPTALDH1A1KMT2A | |
| SCHEMBL19308631 | 0.71 | MAPT (0.55) | MAPTALDH1A1KMT2AGAATSHR | |
| SCHEMBL13057019 | 0.71 | MAPT (0.55) | MAPTALDH1A1KMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154851-A | ANTIDEPRESSANTS, ANTIAGRESSIVE AGENTS | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-05-15 | — | — | US | disclosed |