Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518743 | 0.91 | ABCG2 (0.48) | ABCG2ABCB1ABCC1KDM4EPOLB | |
| SCHEMBL11563586 | 0.88 | HPGD (0.50) | ABCG2ABCB1ABCC1KDM4EPOLB | |
| SCHEMBL11522725 | 0.83 | KDM4E (0.56) | KDM4EPOLBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11516748 | 0.83 | KDM4E (0.49) | ABCG2ABCB1ABCC1KDM4EPOLB | |
| SCHEMBL11520373 | 0.82 | KDM4E (0.45) | ABCG2ABCB1ABCC1KDM4EPOLB | |
| SCHEMBL11519550 | 0.81 | KDM4E (0.53) | KDM4EPOLBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11560846 | 0.80 | HPGD (0.47) | ABCG2KDM4EPOLBALDH1A1TP53 | |
| SCHEMBL11619136 | 0.80 | ABCG2 (0.64) | ABCG2ABCB1ABCC1 | |
| SCHEMBL11560261 | 0.79 | ALDH1A1 (0.53) | ABCB1KDM4EPOLBALDH1A1TP53 | |
| SCHEMBL11559274 | 0.78 | HPGD (0.51) | ABCG2ABCB1ABCC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157334-A | ANTIALLERGENS, SPASMOLYTIC | CARLO ERBA S. P. A. (IT) | 1979-06-05 | — | — | US | claimed |
| US-4157334-A | ANTIALLERGENS, SPASMOLYTIC | CARLO ERBA S. P. A. (IT) | 1979-06-05 | — | — | US | disclosed |