Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.64 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.52 |
| ▸ | TNKS | O95271 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627793 | 0.88 | ABCG2 (0.58) | ABCG2ABCB1ABCC1SIGMAR1TNKS | |
| SCHEMBL11561409 | 0.86 | ABCG2 (0.49) | ABCG2ABCB1ABCC1BCHECNR2 | |
| SCHEMBL11560525 | 0.82 | MAPT (0.53) | ABCG2ABCB1ABCC1SIGMAR1TNKS | |
| SCHEMBL11563586 | 0.81 | HPGD (0.50) | ABCG2ABCB1ABCC1SIGMAR1TNKS | |
| SCHEMBL6176196 | 0.81 | L3MBTL1 (0.59) | ABCG2ABCB1BCHESIGMAR1TNKS | |
| SCHEMBL11518211 | 0.80 | ABCG2 (0.49) | ABCG2ABCB1ABCC1 | |
| SCHEMBL11520373 | 0.79 | KDM4E (0.45) | ABCG2ABCB1ABCC1SIGMAR1TNKS | |
| SCHEMBL31238530 | 0.78 | TNKS (0.66) | ABCG2ABCB1SIGMAR1TNKS | |
| SCHEMBL8934603 | 0.77 | MAPT (0.78) | ABCG2ABCB1BCHETNKS | |
| SCHEMBL10626539 | 0.76 | MAPT (0.73) | ABCB1BCHETNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083953-A | ANTIALLERGENS | CARLO ERBA, S.P.A. (IT) | 1978-04-11 | — | — | US | claimed |
| US-4065467-A | ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS | CARLO ERBA, S. P. A. (IT) | 1977-12-27 | — | — | US | claimed |
| US-4115567-A | TREATMENT OF ALLERGIES | CARLO ERBA S. P. A. (IT) | 1978-09-19 | — | — | US | disclosed |
| US-4083953-A | ANTIALLERGENS | CARLO ERBA, S.P.A. (IT) | 1978-04-11 | — | — | US | disclosed |
| US-4065467-A | ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS | CARLO ERBA, S. P. A. (IT) | 1977-12-27 | — | — | US | disclosed |