Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506155 | 0.83 | PRMT5 (0.54) | ALDH1A1SMN1; SMN2PKMPRMT5MEN1 | |
| SCHEMBL11444406 | 0.81 | L3MBTL1 (0.57) | ALDH1A1SMN1; SMN2PKMLMNAKMT2A | |
| SCHEMBL11520647 | 0.81 | PRMT5 (0.59) | ALDH1A1SMN1; SMN2PKMPRMT5LMNA | |
| SCHEMBL10412483 | 0.80 | MEN1 (0.52) | ALDH1A1SMN1; SMN2PKMPRMT5LMNA | |
| SCHEMBL11693545 | 0.78 | PRMT5 (0.56) | ALDH1A1SMN1; SMN2PKMPRMT5LMNA | |
| SCHEMBL8877177 | 0.78 | PRMT5 (0.50) | ALDH1A1SMN1; SMN2PKMPRMT5MEN1 | |
| SCHEMBL16603956 | 0.78 | BACE1 (0.67) | ALDH1A1PRMT5LMNAMEN1KMT2A | |
| SCHEMBL20853336 | 0.78 | PRMT5 (0.49) | ALDH1A1SMN1; SMN2PKMPRMT5MEN1 | |
| SCHEMBL25145161 | 0.77 | MEN1 (0.51) | ALDH1A1SMN1; SMN2PKMPRMT5LMNA | |
| SCHEMBL8534976 | 0.77 | PRMT5 (0.55) | ALDH1A1SMN1; SMN2PKMPRMT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180503-A | FOR DYEING POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-25 | — | — | US | disclosed |
| US-4124581-A | FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |
| US-4060521-A | POLYAMIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |