Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521198 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11518393 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11857350 | 0.80 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL23169175 | 0.80 | HTT (0.64) | SMN1; SMN2RAB9ANPC1ALDH1A1ALPL | |
| SCHEMBL11517314 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11219207 | 0.78 | KMT2A (0.50) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11517715 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11880686 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL17430271 | 0.77 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11859087 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159281-A | HERBICIDE INTERMEDIATES | CHEVRON RESEARCH COMPANY (US) | 1979-06-26 | — | — | US | disclosed |