Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516079 | 0.86 | LMNA (0.45) | MEN1KMT2APOLBHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL11516834 | 0.85 | LMNA (0.44) | MEN1KMT2APOLBHTR2CMAPT | |
| SCHEMBL11514216 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2APOLBKDM4ENPC1 | |
| SCHEMBL11515494 | 0.82 | BAZ2B (0.43) | POLBHTR2CAKT1NAMPTHRH4 | |
| SCHEMBL11518328 | 0.82 | MAPT (0.45) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL11517624 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL11518462 | 0.79 | MAPT (0.43) | MEN1KMT2APOLBKDM4ERAB9A | |
| SCHEMBL11515001 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL12662820 | 0.77 | BAZ2B (0.43) | MAPTLMNANAMPT | |
| SCHEMBL1994788 | 0.75 | NAMPT (0.38) | POLBKDM4EHTR2CAKT1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | claimed |
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |