Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518649 | 0.91 | TSHR (0.38) | TSHRCYP3A4FAAHMAPTMEN1 | |
| SCHEMBL11529240 | 0.89 | TSHR (0.42) | TSHRCYP3A4FAAHMAPTMEN1 | |
| SCHEMBL11529242 | 0.87 | TSHR (0.41) | TSHRCYP3A4FAAHMAPTMEN1 | |
| SCHEMBL23000641 | 0.87 | TSHR (0.43) | TSHRCYP3A4FAAHMAPTMEN1 | |
| SCHEMBL23000642 | 0.85 | TSHR (0.42) | TSHRCYP3A4FAAHMAPTCNR1 | |
| SCHEMBL4326288 | 0.85 | ALDH1A1 (0.45) | TSHRCYP3A4FAAHMAPTCNR1 | |
| SCHEMBL11520287 | 0.85 | ALDH1A1 (0.42) | TSHRFAAHMEN1THRBKMT2A | |
| SCHEMBL4323428 | 0.78 | TSHR (0.44) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL11520292 | 0.76 | ALDH1A1 (0.38) | TSHRMEN1THRBKMT2AALDH1A1 | |
| SCHEMBL4320762 | 0.76 | TSHR (0.43) | TSHRCYP3A4MAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147686-A | VINYL CHLORIDE RESIN, OXALATES | ARMSTRONG CORK COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4085081-A | \"Smoke-suppressant polyhalocarbon polymer compositions containing as plasticizer an unsaturated derivative of an ester polyol\ | ARMSTRONG CORK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |