Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365041 | 0.93 | TSHR (0.52) | ALDH1A1TSHRATMMEN1THRB | |
| SCHEMBL11517487 | 0.93 | TSHR (0.52) | ALDH1A1TSHRATMMEN1THRB | |
| SCHEMBL10987646 | 0.91 | TSHR (0.64) | ALDH1A1TSHRMEN1THRBHTT | |
| SCHEMBL8984086 | 0.89 | TSHR (0.62) | ALDH1A1TSHRMEN1THRBHTT | |
| SCHEMBL1979194 | 0.88 | TSHR (0.65) | ALDH1A1TSHRATMNAAACYP3A4 | |
| SCHEMBL5501929 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRATMNAAAHPGD | |
| SCHEMBL137155 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRATMNAAAHPGD | |
| SCHEMBL28787473 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRATMNAAAHPGD | |
| SCHEMBL1470113 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRATMMEN1THRB | |
| SCHEMBL5489793 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRATMMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147686-A | VINYL CHLORIDE RESIN, OXALATES | ARMSTRONG CORK COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4085081-A | \"Smoke-suppressant polyhalocarbon polymer compositions containing as plasticizer an unsaturated derivative of an ester polyol\ | ARMSTRONG CORK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |