Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.40 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520044 | 0.84 | HSD17B1 (0.66) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL9755135 | 0.84 | HSD17B1 (0.70) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL11520757 | 0.84 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL14838269 | 0.83 | HSD17B1 (0.42) | HSD17B1ESR1ESR2HSD17B2EP300 | |
| SCHEMBL14832743 | 0.83 | SNCA (0.47) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL11521308 | 0.81 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL11521678 | 0.81 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL11524663 | 0.79 | HSD17B1 (0.55) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL11522286 | 0.78 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2MAPT | |
| SCHEMBL11525349 | 0.78 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | claimed |
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |