Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519550 | 0.91 | KDM4E (0.53) | KDM4EPOLBADORA3ALDH1A1HPGD | |
| SCHEMBL11519582 | 0.88 | TNKS (0.50) | KDM4EPOLBADORA3ALDH1A1HPGD | |
| Isocromil SCHEMBL2109291 | 0.87 | ALDH1A1 (0.55) | KDM4EPOLBALDH1A1HPGDTP53 | |
| Isocromil SCHEMBL11566658 | 0.86 | ALDH1A1 (0.54) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL11519681 | 0.82 | KDM4E (0.48) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL11522725 | 0.81 | KDM4E (0.56) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL11519766 | 0.81 | THRB (0.47) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL11561850 | 0.81 | ALDH1A1 (0.47) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL11518828 | 0.80 | MEN1 (0.47) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL11518979 | 0.80 | KDM4E (0.49) | KDM4EPOLBALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157334-A | ANTIALLERGENS, SPASMOLYTIC | CARLO ERBA S. P. A. (IT) | 1979-06-05 | — | — | US | claimed |
| US-4157334-A | ANTIALLERGENS, SPASMOLYTIC | CARLO ERBA S. P. A. (IT) | 1979-06-05 | — | — | US | disclosed |