Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459340 | 0.83 | CXCR4 (0.46) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL18944448 | 0.81 | CYP2D6 (0.48) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL3027344 | 0.76 | CYP2D6 (0.34) | CYP2D6 | |
| SCHEMBL11518609 | 0.75 | POLB (0.37) | MEN1ADRA2CKMT2AHRH3CYP2D6 | |
| SCHEMBL9339240 | 0.74 | KCNH2 (0.34) | CHRM2CHRM1 | |
| SCHEMBL11044069 | 0.74 | KCNH2 (0.34) | CHRM2CHRM1 | |
| SCHEMBL11519567 | 0.74 | KCNH2 (0.34) | CHRM2CHRM1 | |
| SCHEMBL11518881 | 0.73 | CYP2D6 (0.60) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL3143023 | 0.73 | CYP2D6 (0.68) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL11518108 | 0.72 | FAAH (0.54) | CXCR4MEN1CHRM2CHRM1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177272-A | HYPOTENSIVE, VASODILATION, PARKINSON'S DISEASE | SCIENCE UNION ET CIE (FR) | 1979-12-04 | — | — | US | disclosed |