Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986906 | 0.94 | MAPT (0.54) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL11191264 | 0.89 | MTNR1B (0.52) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL27587753 | 0.88 | CYP3A4 (0.59) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL8306841 | 0.86 | APP (0.58) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL9502179 | 0.85 | SYK (0.47) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL27926957 | 0.84 | TP53 (0.53) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL27934212 | 0.84 | HTT (0.55) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL4050094 | 0.84 | TP53 (0.63) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL146848 | 0.84 | TP53 (0.53) | SYKTP53CYP3A4KMT2AMEN1 | |
| SCHEMBL10411688 | 0.83 | SYK (0.58) | SYKTP53CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144260-A | Production of aluminum salts of N-nitroso-N-alkyl-hydroxylamines | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4082749-A | FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |