Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522485 | 0.93 | CYP2D6 (0.56) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL108678 | 0.80 | KDM4E (0.70) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11520014 | 0.79 | MEN1 (0.60) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11520142 | 0.77 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19481321 | 0.77 | MEN1 (0.61) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Piribedil SCHEMBL5605887 | 0.77 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Piribedil SCHEMBL29359749 | 0.77 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Piribedil SCHEMBL150101 | 0.77 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19481305 | 0.76 | POLB (0.67) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Piribedil SCHEMBL3765569 | 0.76 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177272-A | HYPOTENSIVE, VASODILATION, PARKINSON'S DISEASE | SCIENCE UNION ET CIE (FR) | 1979-12-04 | — | — | US | disclosed |