Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807724 | 0.87 | MAPT (0.56) | MEN1KMT2ARAB9AGAAMAPT | |
| SCHEMBL12127474 | 0.86 | MEN1 (0.66) | MEN1KMT2ARAB9AGAAHTT | |
| SCHEMBL11520703 | 0.85 | MEN1 (0.64) | MEN1KMT2ARAB9AGAAHTT | |
| SCHEMBL11518945 | 0.84 | GAA (0.54) | MEN1KMT2ARAB9AGAAMAPT | |
| SCHEMBL12201220 | 0.83 | L3MBTL1 (0.61) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL11521462 | 0.82 | RAB9A (0.65) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL10914085 | 0.80 | MEN1 (0.77) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL21590314 | 0.80 | MEN1 (0.83) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL8661871 | 0.80 | MEN1 (0.82) | MEN1KMT2ARAB9AGAAMAPT | |
| SCHEMBL8401925 | 0.78 | KMT2A (0.79) | MEN1KMT2ARAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178301-A | 4-(2-(ACETYLTHIO)ACETAMIDO)BENZOIC ACID AS MUCOLYTIC AGENT | MEAD JOHNSON & COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4132802-A | LIQUEFACTION OF MUCUS | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4096277-A | Mucolytic mercaptoacylamidobenzamides and process of using same | MEAD JOHNSON & COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-4005222-A | Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid compounds and process | MEAD JOHNSON & COMPANY (US) | 1977-01-25 | — | — | US | disclosed |