Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL10727608 | 0.96 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL8008161 | 0.93 | — | — | |
| Glycolic Acid SCHEMBL2802374 | 0.89 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL9861748 | 0.89 | — | — | |
| Glycolic Acid SCHEMBL3181599 | 0.89 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL14661856 | 0.89 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL7907676 | 0.89 | — | — | |
| Glycolic Acid SCHEMBL2805397 | 0.89 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL9841034 | 0.89 | CA4 (0.50) | CA4OR51E2CASP1FFAR3HDAC3 | |
| Glycolic Acid SCHEMBL8845857 | 0.89 | CA4 (0.44) | CA4OR51E2CASP1FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142508-A | Method for splicing cables and hot pack for use therein | KAY LABORATORIES, INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4101353-A | Method for splicing cables and hot pack for use therein | KAY LABORATORIES, INC. (US) | 1978-07-18 | — | — | US | disclosed |