Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL134226 | 0.96 | CA4 (0.50) | — | |
| Glycolic Acid SCHEMBL11519785 | 0.93 | CA4 (0.41) | — | |
| Glycolic Acid SCHEMBL9462738 | 0.92 | CA4 (0.47) | — | |
| Glycolic Acid SCHEMBL6810403 | 0.92 | CA4 (0.47) | — | |
| Glycolic Acid SCHEMBL10727608 | 0.88 | CA4 (0.44) | — | |
| Glycolic Acid SCHEMBL991430 | 0.87 | — | — | |
| Glycolic Acid SCHEMBL376971 | 0.87 | CA4 (0.50) | — | |
| Glycolic Acid SCHEMBL15441504 | 0.87 | CA4 (0.50) | — | |
| Glycolic Acid SCHEMBL4522823 | 0.87 | CA4 (0.50) | — | |
| Glycolic Acid SCHEMBL26512 | 0.87 | CA4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6042794-A | SELECTIVE CALCINATION OF MG-CONTAINING MINERALS, SELECTIVE LEACHING OF MAGNESIUM, SEPARATION OF INSOLUBLE IMPURITIES, PRECIPITATION OF MAGNESIUM CHLORIDE HEXAMMONIATE, WHICH IS THERMALLY DECOMPOSED INTO MAGNESIUM CHLORIDE AND AMMONIA | NORSK HYDRO ASA (NO) | 2000-03-28 | — | — | US | disclosed |
| CN-1229400-A | Anhydrous MgCl2Production method of (1) | NORSK HYDRO AS (NO) | 1999-09-22 | — | — | CN | disclosed |
| WO-1998058875-A1 | PROCESS FOR PRODUCING ANHYDROUS MgCl¿2? | NORSK HYDRO ASA (NO) | 1998-12-30 | — | — | WO | disclosed |