Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518266 | 0.87 | CYP2D6 (0.56) | MEN1KMT2APOLBSMN1; SMN2CYP2D6 | |
| SCHEMBL11518615 | 0.85 | CYP2D6 (0.51) | MEN1KMT2APOLBSMN1; SMN2CYP2D6 | |
| SCHEMBL10846038 | 0.84 | MEN1 (0.44) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11517028 | 0.82 | MEN1 (0.59) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11376132 | 0.82 | CYP2D6 (0.40) | MEN1KMT2APOLBCYP2D6CYP1A2 | |
| SCHEMBL11518875 | 0.81 | FAAH (0.47) | FAAHMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10846041 | 0.80 | POLB (0.45) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11517203 | 0.80 | CYP2D6 (0.48) | FAAHMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11379038 | 0.80 | CYP2D6 (0.41) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11518609 | 0.78 | POLB (0.37) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177272-A | HYPOTENSIVE, VASODILATION, PARKINSON'S DISEASE | SCIENCE UNION ET CIE (FR) | 1979-12-04 | — | — | US | disclosed |