Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 7/20 | 0.59 |
| ▸ | HTR1B | P28222 | 4/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27206364 | 0.85 | HTR1A (0.65) | HTR2AHTR1AHTR1BHTR6MTNR1B | |
| SCHEMBL27191685 | 0.85 | HTR1A (0.65) | HTR2AHTR1AHTR1BHTR6MTNR1B | |
| SCHEMBL11524016 | 0.81 | ALDH1A1 (0.55) | HTR1AHTR6MTNR1BHTR1DMAPT | |
| SCHEMBL26508885 | 0.81 | HTR2A (0.64) | HTR2AHTR1AHTR1BHTR6MTNR1B | |
| SCHEMBL32669413 | 0.81 | HTR2A (0.67) | HTR2AHTR1AHTR1BHTR6HTR1D | |
| SCHEMBL32669310 | 0.79 | HTR2A (1.00) | HTR2AHTR1AHTR1BHTR6HTR1D | |
| SCHEMBL11519836 | 0.79 | ALDH1A1 (0.55) | HTR1AHTR1BHTR6MTNR1BHTR1D | |
| SCHEMBL26508872 | 0.79 | HTR2A (0.67) | HTR2AHTR1AHTR1BHTR6MTNR1B | |
| SCHEMBL24723815 | 0.78 | HTR2A (0.97) | HTR2AHTR1AHTR1BHTR6HTR1D | |
| SCHEMBL29633130 | 0.78 | HTR2A (0.97) | HTR2AHTR1AHTR1BHTR6HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |