Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521584 | 0.87 | HSD17B1 (0.51) | HSD17B1ESR1HPGDMAPK1ESR2 | |
| SCHEMBL11520941 | 0.81 | APP (0.56) | HSD17B1ESR1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL11521411 | 0.78 | HSD17B1 (0.48) | HSD17B1ESR1SMN1; SMN2MAPTHPGD | |
| SCHEMBL11521640 | 0.78 | HSD17B1 (0.54) | HSD17B1PTGS2ESR1SMN1; SMN2MAPT | |
| SCHEMBL11522048 | 0.78 | HSD17B1 (0.54) | HSD17B1PTGS2ESR1SMN1; SMN2MAPT | |
| SCHEMBL11523358 | 0.78 | HSD17B1 (0.54) | HSD17B1PTGS2ESR1SMN1; SMN2MAPT | |
| SCHEMBL8481713 | 0.77 | CYP17A1 (0.57) | PTGS2PTGS1SMN1; SMN2MAPTHPGD | |
| SCHEMBL11520185 | 0.77 | HSD17B1 (0.56) | HSD17B1ESR1SMN1; SMN2MAPTNFKB1 | |
| SCHEMBL11522511 | 0.76 | CYP1A1 (0.54) | HSD17B1ESR1SMN1; SMN2MAPTHPGD | |
| SCHEMBL11522025 | 0.76 | HSD17B1 (0.58) | HSD17B1PTGS2PTGS1ESR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | claimed |
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |