Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522048 | 0.89 | HSD17B1 (0.54) | HSD17B1PTPN1HSD17B2ESR1ESR2 | |
| SCHEMBL11523358 | 0.89 | HSD17B1 (0.54) | HSD17B1PTPN1HSD17B2ESR1ESR2 | |
| SCHEMBL11521640 | 0.89 | HSD17B1 (0.54) | HSD17B1PTPN1HSD17B2ESR1ESR2 | |
| SCHEMBL9755135 | 0.83 | HSD17B1 (0.70) | HSD17B1PTPN1IKBKBHSD17B2ESR1 | |
| SCHEMBL11520829 | 0.82 | ESR1 (0.59) | PTPN1IKBKBESR1ESR2TDP1 | |
| SCHEMBL11522511 | 0.81 | CYP1A1 (0.54) | HSD17B1PTPN1HSD17B2ESR1TDP1 | |
| SCHEMBL11522498 | 0.81 | OPRD1 (0.48) | HSD17B1HSD17B2ESR1ESR2RAB9A | |
| SCHEMBL11521584 | 0.80 | HSD17B1 (0.51) | HSD17B1PTPN1HSD17B2ESR1ESR2 | |
| SCHEMBL11520044 | 0.79 | HSD17B1 (0.66) | HSD17B1HSD17B2ESR1ESR2RAB9A | |
| SCHEMBL16011179 | 0.77 | HDAC6 (0.45) | HSD17B1PTPN1IKBKBHDAC6HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | claimed |
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |