Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 11/20 | 0.53 |
| ▸ | CA2 | P00918 | 11/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 8/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.50 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11520162 | 0.83 | MAPT (0.62) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL10869900 | 0.81 | CA1 (0.54) | CA1CA2CA12CA9CA7 | |
| SCHEMBL10049715 | 0.80 | CA1 (0.53) | CA1CA2CA12CA9CA7 | |
| SCHEMBL2740707 | 0.79 | CA1 (0.51) | CA1CA2CA12CA9CA7 | |
| SCHEMBL13566682 | 0.79 | CA1 (0.75) | CA1CA2CA12CA9CA7 | |
| SCHEMBL17428489 | 0.79 | CA1 (0.51) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL11516558 | 0.78 | CA1 (0.48) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL10797653 | 0.78 | CA1 (0.60) | CA1CA2CA12CA9CA7 | |
| SCHEMBL26502909 | 0.77 | MAPT (1.00) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL28226036 | 0.77 | CA1 (0.67) | MAPTCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178301-A | 4-(2-(ACETYLTHIO)ACETAMIDO)BENZOIC ACID AS MUCOLYTIC AGENT | MEAD JOHNSON & COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4132802-A | LIQUEFACTION OF MUCUS | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4096277-A | Mucolytic mercaptoacylamidobenzamides and process of using same | MEAD JOHNSON & COMPANY (US) | 1978-06-20 | — | — | US | disclosed |