SCHEMBL11520186

SCHEMBL11520186

O=C1[CH]C(=O)CC2(C1)CC(=O)[CH]C(=O)C2

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1521386 0.73 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ANPSR1
SCHEMBL133712 0.65
SCHEMBL7170234 0.59
SCHEMBL16269086 0.59
SCHEMBL675775 0.59
SCHEMBL7638036 0.59
SCHEMBL16269303 0.57
SCHEMBL16269738 0.57
SCHEMBL8291815 0.54 ALDH1A1 (0.48) GSK3AGSK3BALDH1A1MEN1KMT2A
SCHEMBL290757 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed