Sugi Predict

Sugi Predict / Compounds / SCHEMBL1521386

SCHEMBL1521386

SCHEMBL1521386

CC1(C)CC(=O)[CH]C(=O)C1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.48
▸ MAPT P10636 3/20 0.45
▸ HPGD P15428 1/20 0.45
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ LMNA P02545 2/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ APEX1 P27695 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8291815 0.81 ALDH1A1 (0.48) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL11520186 0.73 GSK3A (0.32) ALDH1A1MEN1KMT2ANPSR1
SCHEMBL7102666 0.73 ALDH1A1 (0.52) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL22522 0.73 ALDH1A1 (0.52) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL271129 0.71 ALDH1A1 (0.50) ALDH1A1MAPTHPGDMEN1KMT2A
Water SCHEMBL9637163 0.71 ALDH1A1 (0.50) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL2241228 0.71 ALDH1A1 (0.50) ALDH1A1MAPTHPGDMEN1KMT2A
Ammonia Solution, Strong SCHEMBL7735826 0.71 ALDH1A1 (0.50) ALDH1A1MAPTHPGDMEN1KMT2A
Ammonia Solution, Strong SCHEMBL10613596 0.71 ALDH1A1 (0.50) ALDH1A1MAPTHPGDMEN1KMT2A
Ammonia Solution, Strong SCHEMBL1984334 0.71 ALDH1A1 (0.50) ALDH1A1MAPTHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 — — US claimed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 — — EP claimed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 — — CN claimed
WO-2022200208-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2022-09-29 — — WO claimed
WO-2004069200-A2 SPECIFIC INHIBITORS OF NFAT ACTIVATION BY CALCINEURIN AND THEIR USE IN TREATING IMMUNE-RELATED DISEASES THE CBR INSTITUTE FOR BIOMEDICAL RESEARCH, INC. (US) 2004-08-19 — — WO claimed
US-20040002117-A1 Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases CBR INSTITUTE OF BIOMEDICAL RESEARCH, INC., THE 2004-01-01 — — US claimed
EP-0417555-B1 Pentamethine dyes and derivatives BAYER AG (DE) 1993-11-03 — — EP claimed
US-5118814-A Pressure sensitive and heat sensitive recording media BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 — — US claimed
EP-0417555-A1 Pentamethine dyes and derivatives BAYER AG (DE) 1991-03-20 — — EP claimed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 — — EP claimed
US-4054718-A Heat-sensitive recording material containing a malachite green color former CIBA-GEIGY CORPORATION (US) 1977-10-18 — — US claimed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 — — US disclosed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 — — EP disclosed
US-11872262-B2 Means and methods for treating bacterial infections VIB VZW (BE) 2024-01-16 — — US disclosed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 — — CN disclosed
US-4841050-A Carbazole containing benzopyrans BASF AKTIENGESELLSCHAFT (DE) 1989-06-20 — — US disclosed
EP-0236973-B1 BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM BASF Aktiengesellschaft (DE) 1989-06-14 — — EP disclosed
EP-0304613-A1 Benzopyran derivatives BASF Aktiengesellschaft (DE) 1989-03-01 — — EP disclosed
EP-0236973-A2 Benzopyranes and their use in a recording system BASF Aktiengesellschaft (DE) 1987-09-16 — — EP disclosed
US-4054718-A Heat-sensitive recording material containing a malachite green color former CIBA-GEIGY CORPORATION (US) 1977-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002117-A1 Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases NFATC1, CHP1, PPP3R1 ALDH1A1 4881/4885MAPT 3702/4885HPGD 3156/4885
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES HPD, DDT, PPOX ALDH1A1 315/4885MAPT 3582/4885HPGD 280/4885
US-11872262-B2 Means and methods for treating bacterial infections VIP, MMP8, SLC11A2 ALDH1A1 4565/4885MAPT 4028/4885HPGD 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.