Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | THRB | P10828 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | RECQL | P46063 | 7/20 | 0.64 |
| ▸ | BLM | P54132 | 7/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | USP2 | O75604 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | TOP2A | P11388 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Daunomycinone SCHEMBL118279 | 1.00 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL118280 | 1.00 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL30089793 | 1.00 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL9474409 | 0.99 | S100A4 (0.65) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL11700352 | 0.96 | S100A4 (0.62) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL14562280 | 0.90 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL11517177 | 0.90 | S100A4 (0.55) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL12250542 | 0.89 | MEN1 (0.65) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL6668771 | 0.89 | MEN1 (0.57) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL30408780 | 0.89 | MEN1 (0.65) | S100A4MEN1THRBKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161480-A | Intermediates for the synthesis of 4-demethoxydaunorubicin | G. D. SEARLE & CO. (US) | 1979-07-17 | — | — | US | disclosed |