Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | THRB | P10828 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | RECQL | P46063 | 7/20 | 0.64 |
| ▸ | BLM | P54132 | 7/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | USP2 | O75604 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | TOP2A | P11388 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Daunomycinone SCHEMBL118280 | 1.00 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL11520484 | 1.00 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL30089793 | 1.00 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL9474409 | 0.99 | S100A4 (0.65) | S100A4MEN1THRBKMT2ARECQL | |
| Daunomycinone SCHEMBL11700352 | 0.96 | S100A4 (0.62) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL14562280 | 0.90 | S100A4 (0.66) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL11517177 | 0.90 | S100A4 (0.55) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL12250542 | 0.89 | MEN1 (0.65) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL6668771 | 0.89 | MEN1 (0.57) | S100A4MEN1THRBKMT2ARECQL | |
| SCHEMBL30408780 | 0.89 | MEN1 (0.65) | S100A4MEN1THRBKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305104-A | A kind of daunomycinone intermediate | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110305000-A | A kind of daunomycinone midbody compound | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110305001-A | A kind of synthetic method of epirubicin intermediate daunomycinone | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110305103-A | Daunomycinone midbody compound | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110305158-A | A kind of midbody compound of daunomycinone | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110304999-A | A kind of daunomycinone midbody compound | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110305101-A | A kind of daunomycinone midbody compound | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-109942647-A | A kind of synthetic method of epirubicin intermediate epirubicin | 鲁南制药集团股份有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-109293613-A | A kind of epirubicin midbody compound | 鲁南制药集团股份有限公司 | 2019-02-01 | — | — | CN | claimed |
| WO-2013070911-A1 | COMPOUNDS AND METHODS FOR TREATING CYSTIC FIBROSIS | THE MARINE BIOLOGICAL LABORATORY (US) | 2013-05-16 | — | — | WO | claimed |
| EP-0024727-B1 | ANTHRACYCLINE GLYCOSIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-05-26 | — | — | EP | claimed |
| EP-0051280-A1 | Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-05-12 | — | — | EP | claimed |
| EP-0051279-A1 | Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-05-12 | — | — | EP | claimed |
| US-4327029-A | DAUNOMYCINS, ANTITUMOR | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-04-27 | — | — | US | claimed |
| US-4267116-A | AS ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-05-12 | — | — | US | claimed |
| EP-0024727-A1 | Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them | FARMITALIA CARLO ERBA S.p.A. (IT) | 1981-03-11 | — | — | EP | claimed |
| EP-0016157-A4 | 7-0-(2,6-DIDEOXY-ALPHA-L-LYXO-HEXOPYRANOSYL)-DESMETHOXY-ADRIAMYCINONE. | US COMMERCE (US) | 1980-11-14 | — | — | EP | claimed |
| EP-0016157-A1 | 7-0-(2,6-DIDEOXY-ALPHA-L-LYXO-HEXOPYRANOSYL)-DESMETHOXY-ADRIAMYCINONE | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1980-10-01 | — | — | EP | claimed |
| US-4201773-A | ANTIBIOTICS, ANTILEUKEMIA | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-05-06 | — | — | US | claimed |
| WO-1980000305-A1 | 7-0-(2,6-DIDEOXY-A-L-LYXO-HEXOPYRANOSYL)-DESMETHOXYDAUNOMYCINONE,ADRIAMYCINONE,AND CARMINOMYCINONE | US COMMERCE (US) | 1980-03-06 | — | — | WO | claimed |