SCHEMBL115205

SCHEMBL115205

O=C(O)Cc1cc2cc(O)ccc2[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMAD3 P84022 1/20 0.57
FLT3 P36888 8/20 0.54
PDGFRB P09619 2/20 0.54
ABL1 P00519 1/20 0.54
KIT P10721 1/20 0.54
BCR P11274 1/20 0.54
SIRT1 Q96EB6 1/20 0.50
BACE1 P56817 1/20 0.49
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
LMNA P02545 1/20 0.47
GLA P06280 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
PMP22 Q01453 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PDGFRA P16234 1/20 0.47
CA2 P00918 1/20 0.46
NLRP3 Q96P20 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30620163 1.00 SMAD3 (0.57) SMAD3FLT3PDGFRBABL1KIT
Acetic Acid SCHEMBL28006441 0.95 SMAD3 (0.53) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL17165666 0.91 SMAD3 (0.49) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL1332670 0.87 SMAD3 (0.54) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL2031429 0.85 SMAD3 (0.56) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL31026282 0.85 SIRT1 (0.69) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL1331871 0.84 BACE1 (0.48) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL5097277 0.81 SIRT1 (0.74) SIRT1ALDH1A1LMNAPPARGIDO1
SCHEMBL3838663 0.81 TSHR (0.58) FLT3SIRT1ALDH1A1HPGDLMNA
SCHEMBL28689775 0.81 SIRT1 (0.49) FLT3SIRT1ALDH1A1HPGDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5144 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122084713-A Microelectrode, probe and electrochemical detection device 2026-05-26 CN claimed
US-20260091037-A1 METHODS FOR INCREASING SEPIAPTERIN PLASMA EXPOSURE PTC THERAPEUTICS MP INC (US) 2026-04-02 US claimed
EP-3801534-B1 TREATMENT OF PHENYLKETONURIA WITH SEPIAPTERIN PTC THERAPEUTICS MP INC (US) 2026-02-18 EP claimed
US-20250228842-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME Crinetics Pharmaceuticals, Inc. 2025-07-17 US claimed
US-20250205310-A1 METHOD FOR REVERSING BODY-WIDE AGE-ASSOCIATED FUNCTIONAL CHANGES THE CHINESE UNIVERSITY OF HONG KONG (CN) 2025-06-26 US claimed
US-20250195529-A1 COMPOSITIONS AND METHODS FOR INCREASING TETRAHYDROBIOPTERIN PLASMA EXPOSURE PTC THERAPEUTICS MP, INC. 2025-06-19 US claimed
CN-120064627-A Biomarker for diagnosing parkinsonism accompanied with rapid eye movement and sleep behavior disorder and application thereof 上海健康医学院 2025-05-30 CN claimed
EP-4551232-A1 METABOLOMIC IMPROVEMENTS USING RESISTANT STARCH SUPPLEMENTATION Mcpharma Biotech Inc. (CA) 2025-05-14 EP claimed
CN-119716080-A Radioactive enteritis differential metabolite marker based on fecal metabonomics, screening method and application thereof 中山大学附属第六医院 2025-03-28 CN claimed
EP-0781145-B1 DIAGNOSTIC COMPOSITIONS AND THEIR USE FOR THE DETECTION OF CENTRAL NERVOUS SYSTEM ABNORMALITIES OTSUKA PHARMA CO LTD (JP) 2003-07-16 EP claimed
WO-2003049734-A1 COMPOSITIONS COMPRISING EPOTHILONES AND THEIR USE FOR THE TREATMENT OF CARCINOID SYNDROME NOVARTIS AG (CH) 2003-06-19 WO claimed
US-20030022390-A1 Method and kit for making interfering substances in urine undetectable SPECTRUM LABORATORIES INC. 2003-01-30 US claimed
US-20020182600-A1 Method for assaying biological and other constituents using synthetic nucleounits in lateral flow, liquid, and dry chemistry techniques SMITH JACK V (US) 2002-12-05 US claimed
EP-0452765-B1 Pharmaceutical composition and medical uses of dioxopiperidine derivatives, especially as immune response potentiators, antiviral and antibacterial agents BTG INT LTD (GB) 1999-10-20 EP claimed
US-5916537-A Diagnostic and diagnosis method for central nervous abnormality and phenylketonuria OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1999-06-29 US claimed
US-5270215-A Colorimetric method for determination of 5-hydroxyindoleacetic acid PINCUS, MATTHEW R. 1993-12-14 US claimed
EP-0452765-A2 Pharmaceutical composition and medical uses of dioxopiperidine derivatives, especially as immune response potentiators, antiviral and antibacterial agents BTG INTERNATIONAL LIMITED (GB) 1991-10-23 EP claimed
US-4918084-A ANXIOLYTIC AGENTS; BENZODIAZEPINE INVERSE AGONIST ANTAGONISTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-04-17 US claimed
EP-0216555-A2 Use of dioxopiperidine derivatives in the treatment of anxiety, for the reduction of chronic abnormally high brain levels of serotonin or 5-hydroxy-indoleacetic acid, and in the treatment of bacterial or viral infections BTG INTERNATIONAL LIMITED (GB) 1987-04-01 EP claimed