SCHEMBL30620163

SCHEMBL30620163

O=C(O)Cc1cc2cc(O)ccc2[nH]1.O=C(O)Cc1cc2cc(O)ccc2[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMAD3 P84022 1/20 0.57
FLT3 P36888 8/20 0.54
PDGFRB P09619 2/20 0.54
ABL1 P00519 1/20 0.54
KIT P10721 1/20 0.54
BCR P11274 1/20 0.54
SIRT1 Q96EB6 1/20 0.50
BACE1 P56817 1/20 0.49
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
LMNA P02545 1/20 0.47
GLA P06280 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
PMP22 Q01453 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PDGFRA P16234 1/20 0.47
CA2 P00918 1/20 0.46
NLRP3 Q96P20 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115205 1.00 SMAD3 (0.57) SMAD3FLT3PDGFRBABL1KIT
Acetic Acid SCHEMBL28006441 0.95 SMAD3 (0.53) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL17165666 0.91 SMAD3 (0.49) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL1332670 0.87 SMAD3 (0.54) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL2031429 0.85 SMAD3 (0.56) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL31026282 0.85 SIRT1 (0.69) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL1331871 0.84 BACE1 (0.48) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL5097277 0.81 SIRT1 (0.74) SIRT1ALDH1A1LMNAPPARGIDO1
SCHEMBL3838663 0.81 TSHR (0.58) FLT3SIRT1ALDH1A1HPGDLMNA
SCHEMBL28689775 0.81 SIRT1 (0.49) FLT3SIRT1ALDH1A1HPGDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114569633-B Intestinal selective chelators for the treatment and prevention of autism and related disorders 轴向治疗公司 2023-11-17 CN disclosed