Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135459 | 0.90 | TSHR (0.52) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL9321905 | 0.84 | THRB (0.55) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL383961 | 0.83 | TSHR (0.59) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL13950019 | 0.82 | THRB (0.53) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL16268078 | 0.81 | TSHR (0.49) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL331327 | 0.81 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL3280966 | 0.81 | TSHR (0.53) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL18094662 | 0.81 | HRH3 (0.50) | TSHRTHRBALDH1A1HRH3 | |
| SCHEMBL382201 | 0.81 | TSHR (0.61) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL2043006 | 0.81 | TSHR (0.37) | TSHRTHRBTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163092-A | QUATERNIZED MONOMER, CROSS-LINKING AGENT | PLASTOMEDICAL SCIENCES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4060678-A | Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4058491-A | Cationic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-15 | — | — | US | disclosed |