Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297877 | 0.86 | ACE2 (0.30) | ACE2 | |
| SCHEMBL31279666 | 0.71 | DNTT (0.32) | GAAPTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL9678949 | 0.68 | DNTT (0.33) | PTPN1CYP19A1DNTTPOLBPOLA1 | |
| SCHEMBL4188419 | 0.62 | — | — | |
| SCHEMBL31372642 | 0.60 | LIPG (0.33) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2351195 | 0.58 | TSHR (0.44) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL7724036 | 0.56 | TSHR (0.47) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6472048 | 0.55 | TSHR (0.40) | — | |
| SCHEMBL10869939 | 0.55 | TSHR (0.40) | — | |
| SCHEMBL1261809 | 0.55 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306829-A | Hydroxyxanthones | CIBA-GEIGY CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |