Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.36 |
| ▸ | CA2 | P00918 | 10/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979860 | 1.00 | CA1 (0.36) | CA1CA2THRBSTSMAOB | |
| SCHEMBL28997433 | 0.91 | THRB (0.35) | CA1CA2THRBMAOBHDAC3 | |
| Hydrochloric Acid SCHEMBL11522729 | 0.90 | THRB (0.34) | CA1CA2THRBMAOBHDAC3 | |
| SCHEMBL28357377 | 0.84 | CA1 (0.38) | CA1CA2STS | |
| SCHEMBL11123042 | 0.81 | PKM (0.46) | CA1CA2STS | |
| SCHEMBL29971333 | 0.80 | CA1 (0.39) | CA1CA2STS | |
| SCHEMBL29048865 | 0.80 | CA1 (0.39) | CA1CA2STS | |
| SCHEMBL11524066 | 0.80 | CA1 (0.42) | CA1CA2STS | |
| SCHEMBL11520579 | 0.80 | CA1 (0.42) | CA1CA2STS | |
| SCHEMBL11519176 | 0.80 | CA1 (0.42) | CA1CA2STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163754-A | Fluorinated sulfonamides | ICI AMERICAS INC. (US) | 1979-08-07 | — | — | US | claimed |
| US-4163754-A | Fluorinated sulfonamides | ICI AMERICAS INC. (US) | 1979-08-07 | — | — | US | disclosed |