Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390193 | 0.94 | PTGS1 (0.66) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11840934 | 0.91 | PTGS1 (0.80) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11502736 | 0.89 | MAPT (0.65) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11215786 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11841581 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11519106 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL10811905 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL10811911 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11444166 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11061430 | 0.88 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |