Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339948 | 0.85 | SRD5A2 (0.53) | MAPTHPGDKMT2AEPHX2NR1H4 | |
| SCHEMBL779449 | 0.85 | MAPT (0.45) | MAPTHPGDKMT2ARAB9AEPHX2 | |
| SCHEMBL11517109 | 0.84 | ALDH1A1 (0.54) | MAPTHPGDKMT2ARAB9AEPHX2 | |
| SCHEMBL29764513 | 0.83 | MAPK1 (0.52) | HPGDKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL3121853 | 0.76 | MAPT (0.44) | MAPTHPGDKMT2ARAB9AEPHX2 | |
| SCHEMBL11520031 | 0.75 | MAPK1 (0.44) | HPGDKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL677816 | 0.74 | MAPT (0.50) | MAPTHPGDKMT2ARAB9AEPHX2 | |
| SCHEMBL11278492 | 0.74 | MAPT (0.51) | MAPTHPGDKMT2ARAB9AEPHX2 | |
| SCHEMBL9472225 | 0.74 | HPGD (0.50) | MAPTHPGDKMT2ARAB9AEPHX2 | |
| SCHEMBL397829 | 0.74 | EPHX2 (0.65) | MAPTHPGDKMT2ARAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152293-A | MULTISTAGE PREPARATION AND PURIFICATION OF P-DIISOPROPYLBENZENE MONOHYDROPEROXIDE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-05-01 | — | — | US | disclosed |