Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519311 | 0.86 | CA2 (0.52) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11518673 | 0.86 | MEN1 (0.63) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11519385 | 0.85 | MEN1 (0.58) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11522926 | 0.85 | ENPP1 (0.60) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11522507 | 0.84 | CA1 (0.62) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11521863 | 0.84 | CA1 (0.55) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11519505 | 0.82 | CA1 (0.56) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11518193 | 0.82 | MEN1 (0.69) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11451134 | 0.82 | LTA4H (0.59) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL11521263 | 0.82 | CA2 (0.59) | CA1CA2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |