Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11519688 | 0.99 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTTSHRGAA | |
| Hydrochloric Acid SCHEMBL11519881 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL11524016 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTTSHRGAA | |
| Hydrochloric Acid SCHEMBL11522973 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL11520500 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL11519836 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL11517681 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL11519362 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTTSHRGAA | |
| Hydrochloric Acid SCHEMBL11524195 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL11520569 | 0.78 | HSD17B10 (0.71) | ALDH1A1KDM4EMAPTTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |