SCHEMBL11521069

SCHEMBL11521069

IC(I)c1cccc(C(I)I)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 3/20 0.39
PGK2 P07205 3/20 0.39
DPP4 P27487 2/20 0.32
F2 P00734 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MDM4 O15151 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
TYR P14679 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
CA5A P35218 1/20 0.30
HTT P42858 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17468939 0.81 CYP3A4 (0.52) TSHRKDM4EALDH1A1CA1CA2
SCHEMBL329655 0.76
SCHEMBL15196000 0.75 CYP3A4 (0.39) ALDH1A1TP53CYP3A4MAPTHPGD
SCHEMBL22288271 0.75 HDAC4 (0.37) PGK1PGK2KDM4EMDM4ALDH1A1
SCHEMBL8715735 0.71 DPP4 (0.43) DPP4F2TSHR
SCHEMBL8716106 0.71 DPP4 (0.43) DPP4F2TSHR
SCHEMBL8717286 0.71 DPP4 (0.43) DPP4F2TSHR
SCHEMBL7942691 0.70
SCHEMBL19424129 0.69 HDAC4 (0.47) TSHRKDM4EMDM4ALDH1A1CA1
SCHEMBL23343758 0.68 PGK1 (0.39) PGK1PGK2KDM4EMDM4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed