Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075199 | 0.89 | CTSL (0.67) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL11522377 | 0.87 | ATM (0.54) | CTSLCTSSPPARGATMKLK1 | |
| SCHEMBL10969427 | 0.85 | CTSL (0.60) | CTSLCTSSATMALDH1A1CYP1A2 | |
| SCHEMBL7719287 | 0.78 | ATM (0.77) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL434233 | 0.78 | ATM (0.77) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL3255533 | 0.78 | ATM (0.77) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL1362502 | 0.78 | ATM (0.77) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL12033400 | 0.77 | ATM (0.60) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL12033397 | 0.77 | ATM (0.60) | CTSLCTSSPPARGATMALDH1A1 | |
| SCHEMBL12033401 | 0.77 | ATM (0.60) | CTSLCTSSPPARGATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |