Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | KLK8 | O60259 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17776392 | 0.89 | ATM (0.65) | ATMCTSLCTSSKLK8F2 | |
| SCHEMBL18925994 | 0.89 | ATM (0.65) | ATMCTSLCTSSKLK8F2 | |
| SCHEMBL11522376 | 0.87 | CTSL (0.56) | ATMPPARGCTSLCTSSKLK1 | |
| SCHEMBL16766403 | 0.79 | ATM (0.62) | ATMPPARGCTSLCTSS | |
| SCHEMBL3255533 | 0.78 | ATM (0.77) | ATMPPARGCTSLCTSS | |
| SCHEMBL7719287 | 0.78 | ATM (0.77) | ATMPPARGCTSLCTSS | |
| SCHEMBL1362502 | 0.78 | ATM (0.77) | ATMPPARGCTSLCTSS | |
| SCHEMBL434233 | 0.78 | ATM (0.77) | ATMPPARGCTSLCTSS | |
| SCHEMBL9457091 | 0.78 | ATM (0.76) | ATMPPARGCTSLCTSS | |
| SCHEMBL9457096 | 0.78 | ATM (0.76) | ATMPPARGCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |