Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520617 | 0.79 | MTNR1B (0.34) | LMNAALDH1A1MAPTHTTMEN1 | |
| SCHEMBL11011905 | 0.78 | TRPV1 (0.31) | TRPV1 | |
| SCHEMBL21024034 | 0.76 | CREBBP (0.40) | TRPV1ATAD2MTNR1AMTNR1B | |
| SCHEMBL11011908 | 0.75 | TRPV1 (0.34) | TRPV1ATAD2ACHE | |
| SCHEMBL11523030 | 0.75 | ITGAV (0.38) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30558705 | 0.74 | HDAC1 (0.46) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL3312236 | 0.74 | HDAC1 (0.46) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11522209 | 0.73 | TRPV1 (0.32) | TRPV1 | |
| SCHEMBL907604 | 0.72 | MEN1 (0.43) | LMNASMN1; SMN2MEN1KMT2AMTNR1A | |
| SCHEMBL29704388 | 0.72 | MEN1 (0.43) | LMNASMN1; SMN2MEN1KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |