Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521126 | 0.95 | PTGS2 (0.51) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11519435 | 0.94 | LMNA (0.57) | PTGS2CNR2CNR1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL11517541 | 0.93 | LMNA (0.56) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11521766 | 0.93 | LMNA (0.57) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11523590 | 0.90 | PTGS2 (0.65) | PTGS2CNR2CNR1LMNACYP1A2 | |
| SCHEMBL11523712 | 0.90 | LMNA (0.52) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11517720 | 0.89 | PTGS2 (0.55) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11518381 | 0.89 | PTGS2 (0.53) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11522839 | 0.89 | CNR2 (0.49) | PTGS2CNR2CNR1TSHRLMNA | |
| SCHEMBL11521240 | 0.89 | AKR1C3 (0.56) | PTGS2CNR2CNR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |