Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414651 | 0.95 | HSP90AA1 (0.43) | HSP90AA1EGFRKDM4EMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL14811082 | 0.93 | HSP90AA1 (0.42) | HSP90AA1EGFRKDM4EMEN1NPC1 | |
| SCHEMBL27716419 | 0.82 | MAOA (0.45) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL2163438 | 0.80 | KDM4E (0.47) | KDM4EMEN1ALDH1A1KMT2AMAP4K4 | |
| SCHEMBL31097206 | 0.80 | MAP4K4 (0.35) | KDM4EMEN1NPC1ALDH1A1TP53 | |
| SCHEMBL14425841 | 0.78 | HSP90AA1 (0.38) | HSP90AA1 | |
| SCHEMBL31158156 | 0.78 | MAP4K4 (0.52) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL17546483 | 0.77 | ADRB2 (0.41) | HSP90AA1KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL2640699 | 0.75 | CYP19A1 (0.47) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL19413584 | 0.75 | NPC1 (0.36) | HSP90AA1NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159262-A | POLYIMIDES, POLYBENZIMIDAZOLES, POLYQUINOXALINES, POLYIMIDAZOPYRROLONES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR, NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4061856-A | TO 1,3,5-TRIAZINES, SULFONIC, SULFINIC, PHOSPHONIC OR PHOSPHINIC ACID OR METAL ACETYLACETONATE CATALYST | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1977-12-06 | — | — | US | disclosed |